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medicine

Good Pill Hunting: How Biotech Fell In Love With Beantown

Tomas Kellner
May 14, 2018
Boston is home to what might be the world’s premier biotechnology cluster. It includes big pharmaceutical companies such as Pfizer and Sanofi, plucky upstarts such as Editas Medicine, a gene-editing company, and many research labs. GE’s own biotechnology business, GE Healthcare Life Sciences, recently moved its U.S. headquarters into the area.
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Genomics

The Real Hurdles In Taking CRISPR From Bench To Bedside

Kevin Doxzen Innovative Genomics Institute
September 06, 2017

In only a few years, a novel genome engineering technology, known as CRISPR, has gone from obscurity to revolutionary. The world is eager to see how this tool could cure a range of deadly genetic diseases. Eyes remain fixated on grandiose headlines, but the public may not be aware of the long road ahead for CRISPR clinical trials, writes Kevin Doxzen of the Innovative Genomics Institute. He explains what needs to happen before CRISPR will make it into your local neighborhood hospital.

 
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Cell Therapy

Pump Up The Volume: ‘Genome Sculpting’ Could Help Scale Biotherapeutic Medicine

March 15, 2017

The first biopharmaceutical drugs using complex organic molecules produced by genetically modified cells to deliver more efficient therapies have already started to write the next chapter of medicine. Treatments designed from lab-made versions of large proteins are now being used to treat cancers and autoimmune disorders like multiple sclerosis. Research shows they might also do well against infectious diseases.

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Biologics

These Synthetic Snippets Of DNA Could Make A New Generation Of Drugs Available To All

January 24, 2017
There’s more to protein than steak, eggs and the South Beach Diet. The complex molecules encoded by our DNA are the workhorses of our cells, being responsible for growth, maintenance and repair.
The human body holds many thousands of different proteins, and even small typos in the genetic code can lead to diseases and conditions such as diabetes, hemophilia, dwarfism and many others.
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Biologics

Ireland Is Building A Hub For Next-Gen Drugs

Dorothy Pomerantz
October 11, 2016
Ireland is a country perhaps best known for pints of the black stuff and rugged emerald vistas and James Joyce’s evergreen “Ulysses.” In medical circles, it also has a reputation as a pharmaceutical hub. With a population of just 4.5 million, Ireland is punching far above its weight in this industry.
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Biologics

Gone Protein Fishing: Sweden Is Building A Hub For Medicine’s Future In The Home Of Its Past

July 20, 2016
The Swedish town of Uppsala has been a center of medical innovation for the past 350 years. In 1663, the University of Uppsala opened an anatomical theatre built into the cupola of the Gustavianum, the main building on the Uppsala University campus. Inside, future doctors and also the paying public watched from narrow, tiered, octagonal balconies as professors dissected executed criminals and animals.
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Biologics

Think Inside The Box: Pfizer Will Use GE's Mobile Biotech Factory To Make Next-Generation Drugs In China

June 30, 2016
Americans and Europeans are most likely to die from heart disease. But in China, the leading cause of death is cancer. The disease killed nearly 3 million Chinese in 2015 alone and the country's doctors have few drugs available to fight the epidemic. As grim as the numbers look, they could soon start changing. That's because healthcare reforms recently enacted by the Chinese government support local production of a next-generation class of drugs called biopharmaceuticals and new, flexible drug production methods.
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Biologics

Depeche Module: This Factory On Wheels Can Make The Latest Drugs In Distant Markets

May 15, 2016
The first GE engines used a radial — also called centrifugal — turbine to compress air streaming inside the engine and help it generate thrust. It was similar in design to older technology GE was using for turbo superchargers. Back at Lynn, Sorota started working on an engine with an axial turbine that pushed air through the engine along its axis. “The Whittle engine, when we took apart the compressor, was like a vacuum cleaner compressor,” he says. “It had a two-sided impeller that was very inefficient.
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