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Human Protein Atlas Charts the Road to Personalized Medicine

August 09, 2015
Over a decade ago, the Human Genome Project gave us the first blueprint of our genetic code, opening the door to a future where medical interventions could be personalized for each patient’s genetic composition. Today, programs like the Human Protein Atlas are zooming in even deeper, mapping out not just the DNA that defines our bodies, but also the building blocks – specifically, the proteins – that make them tick (or sick).
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Science of Superheroes: Swedish Scientists Make Amazing Spider Silk from Modified E.coli Bacteria

March 15, 2015
If you live in a house, one of the most amazing materials known to humans is likely languishing in a dark corner of your basement. Spider webs and especially the draglines that form their structure are made from silk threads extruded by arachnids that can be several times tougher than Kevlar and stronger than steel by weight, but also extremely stretchy. Spider silk also has anti-bacterial properties, which may have led Greek and Roman soldiers to use it as wound dressing.
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Bees, Shoots, and Leaves: Amazing Adventures in the Microworld

March 09, 2015
One day two years ago, Gary Sarkis brought a bee’s leg to work. The leg was part of his daughter’s science project and Sarkis, who builds scientific microscopes at GE Healthcare Life Sciences for a living, wanted to take a look with a new imaging machine he and his colleagues have developed. “My daughter and I had studied the leg with her toy microscope at home,” Sarkis says. “We spent a lot of quality time together moving it around and getting it in focus.
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New Class of Personalized Drugs Will Fight Cancer, Immune Disorders. But Making Them is not Easy

March 03, 2015
For millennia, sick people swallowed simple chemicals to get better. From botanical remedies used by people in ancient Mesopotamia, to penicillin, most common drugs are built from molecules with a few dozen atoms that are relatively easy to make.But a new class of medicines made from strings of complex proteins is now leading the charge against disease.
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Will Digital Pathology Retire the Microscope?

January 30, 2015
Digital technology is changing medicine, but many pathologists still use old-fashioned microscopes to ply their trade. They load them with tissue samples, analyze them through the eyepiece and dictate findings to a voice recognition system or an administrative assistant.
It can be a pain. “Every time I reach for a new slide, I have to take my eyes off the lens and check the forms for that case,” says Ian Cree, professor of pathology at Warwick Medical School in Coventry, UK. “You can get a sore neck from hours at the microscope.”
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No Cure But a Wish to Know: We Want to Know if Brain Disease Will Strike

August 19, 2014

There is no cure for Alzheimer’s disease, no definitive test and no way to prevent it. Yet when asked, an overwhelming number of people around the world say they want to know whether they are at risk. “I was surprised by the consistency and strength of that need,” says Ben Newton, who leads the neurology unit at GE Healthcare Life Sciences. “This strength of feeling is rare for a disease that we cannot treat.”

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Junk DNA Could Be Hiding Cancer-Causing Genes

July 29, 2014
Researchers at the Karolinska Institutet’s SciLifeLab in Stockholm recently found almost a hundred new protein-coding regions in parts of the human genome that previously seemed to lack any purpose and were referred to as junk DNA. Some of these genes are so-called pseudogenes, which may be linked to cancer.
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OMG! Super-Resolution Microscope Shines Light on Superbugs, Cancer and Drug-Resistant Slime

March 11, 2014
Researchers call it the “OMG” microscope. They use the machine, whose proper name is DeltaVision OMX*, to study malaria parasites worming their way into red blood cells, see how the HIV virus jumps from a cell to cell, and look for weak spots in the defenses of dangerous superbugs like MRSA and drug-resistant slime.
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