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Circuitry of Cancer

Christoph Hergersberg, Global Technology Leader for Biosciences, was formerly with Amersham. Sitting in one of the bio-labs in upstate New York, he gives an overview of the Biosciences Technology Organization and how a single cell can help cure, treat and diagnose cancer.

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[[Circuitry of Cancer: GE's Biosciences Technology Organization 5th anniversary.]]

[[Christoph Hergersberg - Global Technology Leader for BioSciences]]

[My name is Christoph Hergersberg, and I'm the global technology leader for Biosciences,]

[a global technology organization in Niskayuna, New York at GE Global Research.]

[Before the biosciences organization was founded, global research ]

[and GE as a company, was known more for its engineering, and not for its biology.]

[Now, we've broadened the space for GE to also tap into the space of biology,]

[mostly in the healthcare, but also in other industries. ]

[Right now we are in one of the biosciences labs here.]

[Biosciences works on 5 big domains.]

[One is proteins and genes.]

[Another one is molecular imaging agents and imaging agents,]

[broad diagnostics like in vitro diagnostics.]

[Then we have clinical analysis and translational medicine,]

[and last but certainly not least, we have regenerative medicine and cell technologies.]

[Talking about cell technologies a little bit, what you see here is basically]

[analytical work going on where you take cells.]

[You take the cells, you harvest them, and you analyze them then here biochemically]

[to find out what's going on in the cell.]

[We can do that in a lot of different ways for a lot of different purposes.]

[For instance, in pathology, we are trying to find out what does a cancer cell do different]

[than another normal cell.]

[A cancer cell most notably grows without control,]

[and there are certain molecular mechanisms that tell the cell to ignore everything else]

[and just grow.]

[More and more we are understanding these molecular mechanisms,]

[and the drug industry is tailoring very specific drugs against very specific components]

[of the cancer cell, and by doing that, they can very specifically inhibit the cancer growth.]

[What we are trying here is also to understand these processes and to highlight them,]

[so that you can select the right patient for the right drug.]

[We have seen with other diseases, most notably infectious diseases, ]

[that they became from a death threat, or a death verdict, to become a chronic disease.]

[Cancer, in certain instances, has already become more of a chronic disease]

[that you can manage.]

[The more we understand the molecular mechanisms of cancer,]

[we can cure it in many instances.]

[We can avoid it in other instances, and if both fail, we can manage the disease,]

[and make it a chronic disease that the patient live with for many more longer years. ]

[The overarching connection between all of these programs is that we're using ]

[our biomedical expertise, our applications knowledge, to enable engineering]

[for new products in the healthcare space and in other areas. ]

[The true value of global research for GE is really the interdisciplinary atmosphere.]

[If I was outside, I would be just another biologist doing biomedical research,]

[but here I'm enabling so much more.]

[This is an industrial research lab.]

[You have something that shows impact.]

[You have a purpose in what you do because you see it's going to be applied.]

[You see an optical imaging agent, a contrast agent,]

[a pathology technology being applied for a patient to improve their disease. ]

[As I look forward, I think healthcare is under so much pressure to do something better.]

[We will play a role in making it more effective and with that, more cost effective.]