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$1,000 genome

GE bio-scientists work to sequence human genomes for $1,000 each.

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[[$1000 genome: GE bio-scientists work to sequence human genomes for $1000 each]]

[[Produced by Vivek Kemp for GE]]

[[male narrator] Biologists at GE's Global Research Center in upstate New York]

[are working on mapping a human genome for $1000.]

[The basic building block of every living organism,]

[the genome is the key to personality traits, to disease,]

[and even to when your hair is going to go gray.]

[Your genome is the DNA that your mom gives you half of what you have,]

[and your dad gives you the other half.]

[[GE Healthcare - John Nelson, GE Global Research Center]]

[[narrator] John Nelson is leading GE's team.]

[[Nelson] That's why you have characteristics of both your mother and your father,]

[your DNA in every cell of your body, you have the same DNA,]

[and the DNA is kind of like a big book, and the contents of the book is a story]

[that's made up of 4 letters: G's, A's, T's and C's, ]

[and the order of those letters spell out words and sentences and paragraphs,]

[and the words and the sentences and the paragraphs are genes]

[that are in your chromosomes.]

[It's a huge tool for the medical profession]

[if sequencing becomes so inexpensive that they can do it on all their data sets]

[and try to determine whether or not there are any genetic links]

[to whatever it is that the doctor studies. So it starts out in the research lab.]

[We have to provide them the tools to get the cheap sequence done.]

[What they really would like to have is the sequence from everybody,]

[so we can compare their medical histories with their sequence,]

[to find out if there are any correlations between the sequence that they have]

[at a specific gene, and how they respond to a drug, whether or not they are]

[predisposed to a certain disease, just to tell what kind of traits]

[that that person might end up having as they grow.]

[[narrator] Understanding what mom and dad give us ]

[could help doctors save our lives, he says. ]

[[Nelson] So, my father died of prostate cancer.]

[Did he have a genetic predisposition to it which killed him at the age of 56,]

[and do I have that in myself? ]

[Well, if we could sequence him and figure out what it was]

[that caused him to get prostate cancer at such a young age,]

[do I have that same marker, that same DNA sequence?]

[[narrator] Still, for potential benificiaries of this technology,]

[there are substantial fears about privacy.]

[[Nelson] The ethics of sequencing a human genome is serious,]

[and it is currently under great debate within the government as to how ]

[that whole process is going to be regulated. ]

[There are currently bills that have passed that make it illegal]

[for health insurance companies to refuse to cover you based on]

[your genetic sequences.]

[It is illegal for employers to fire or not hire you]

[as a result of your DNA sequence. ]

[You know, the goal is for people to get a confidential report]

[from their doctor on what the result of the test was.]

[[narrator] For GE Reports, this is Vivek Kemp. ]

[[GE - imagination at work]]